In medicine, the time taken for a test to detect a particular disease (especially an infectious disease) is the time elapsed between the first infection and the time when the test can reliably detect that infection. For antibody-based tests, the window period depends on the time required for seroconversion. During the period from HBsAg to HBsAb seroconversion, IgM Anti-Core (HBc-IgM) is the only detectable antibody. HBV DNA can also be positive. This period does not occur in people who develop chronic hepatitis B, i.e. who have detectable HBV DNA for more than 6 months (HbsAg remains positive), or in people who develop isolated HBcAb positivity, i.e. who lose HBsAg but do not develop HBsAb (HBV DNA may or may not remain positive). [3] If a user or application sends more than 10 requests per second, other requests from the IP address may be restricted for a short period of time. Once the request rate drops below the threshold for 10 minutes, the user can continue to access the content on

This SEC practice is designed to limit excessive automated searches to and is not intended or should not affect individuals who visit the site. Two periods can be called the window period of hepatitis B infection: The representative of the Selling Group must notify the Buyer at least one hundred and eighty (180) days prior to the first day of the Target Period of a ninety (90) day period during the Target Period during which the Selling Group intends to commence operations (the “First Window Period”). The window of opportunity for HIV can be up to three months, depending on the method of testing and other factors. RNA-based HIV tests have the lowest window period. Modern and accurate testing capabilities can shorten this period to 25 days, 16 days, or even just 12 days, depending on the type of test and the quality of its management and interpretation. [1] [2] In medicine, the time window for a test to detect a particular disease is the time between the first infection and the time when the test can reliably detect that infection. For antibody-based tests, the window period depends on the time required for seroconversion. The window period is important for epidemiology and safer sex strategies, as well as for blood and organ donation, because during this period, an infected person or animal cannot be recognized as infected, but it is still capable of infecting other people. For this reason, the most effective disease prevention strategies combine screening with a wait time longer than the test time window.

The window period generally begins on the day Janus Henderson publicly announces its quarterly results and ends at the end of each quarter. Unauthorized attempts to upload information and/or alter information to any portion of this website are strictly prohibited and liable to prosecution under the Computer Fraud and Abuse Act of 1986 and the National Information Infrastructure Protection Act of 1996 (see 18 U.S.C. §§ 1001 and 1030). You can request trading of JHG shares only during the window period. Please report your traffic by updating your user agent to include company-specific information. Note that this policy may change as the SEC maintains to ensure that the site works efficiently and remains available to all users. For more information, see the SEC`s website privacy and security policy. Thank you for your interest in the U.S. Securities and Exchange Commission.

RSU shares (less applicable withholding tax) will be delivered in respect of your outstanding RSUs fairly promptly (but not more than 30 business days) after the delivery date, which is the first business day of the third quarter of the Corporation`s fiscal year that falls within a window period of the year following the year in which you cease to be a director of the Board. By using this website, you consent to security monitoring and auditing. For security reasons and to ensure that the public service remains accessible to users, this government computer system uses network traffic monitoring programs to identify unauthorized attempts, upload or modify information, or otherwise cause damage, including attempts to deny service to users. Provided, however, that in the event of involuntary termination of the employee`s employment relationship without cause during the window period (as described in paragraph c.iv.